Biodegradable Polymers

Biodegradable Polymers

Applications: orthopedic fixation, drug delivery, TE scaffolds

Biodegradation:

• Define:

• Mechanisms (“how”):

  - via hydrolytic, enzymatic, or oxidative cleavage

  - our discussion is limited to hydrolytic cleavage or bond “hydrolysis”

  What bonds can be hydrolyzed (broken by hydrolysis)?

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